What really happens in the dermis? One of the most relevant advances in recent scientific literature concerns the increasingly precise understanding of the biological dynamics of tattoo pigment. Contrary to the intuitive assumption that ink remains statically “deposited” in the skin, histological evidence demonstrates that tattoo pigment localizes within the dermis, where it is primarily engulfed by dermal macrophages and fibroblasts¹. This point is fundamental: tattoos do no