This contribution is the result of the research work of Dr. Silvia Bianchi, member of the Agorà Anti-Aging Medicine Focus Group, and represents one of the first concrete outcomes of the group's shared scientific activity. The dossier presents a systematic review of the recent literature (2019–2024) on intravenous anti-aging therapy with NAD⁺ and glutathione, with the aim of providing an evidence-based overview for aesthetic physicians, endocrinologists and specialists in rege